Basic Information
VIS ID
TVIS10018692
Fusion event
HBV-TENM2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1784
Integrated sequence
TCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCT| |GTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGC
Host Sequence
Chromosome
chr5
Cytoband
q34
Reference genome
GRCh37.55
Start
166540739/167113734 (Hg38)
End
166540744/167113739 (Hg38)
Location type
Intronic
Target gene
TENM2
Nearest miRNA
hsa-mir-10397/Upstream/6628284; hsa-mir-103a-1/Downstream/1052106;
Nearest TSS
ENST00000502646/Upstream/187364; ENST00000517586/Downstream/5846;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/135047, chr5-CpG: 39/Downstream/744795
Nearby gene
LOC101927908
Upstream sequence
aggagtaaccccttttgcttggctctcatacctgcctctatgtaaggtgtgcctttcaccttctgccatgattgtgaggcttcctcagccacatagaact
Downstream sequence
TGATGACAAAAGCAATACATATGCATAGAAAATTTATAAAATATAAGGGGGTATTTTCCCTCTTCACATCCAAAGATAACCATGGTTAACTGTCTGATCC
Target sequence
TATTT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate