Basic Information
VIS ID
TVIS10018696
Fusion event
HBV-chr7 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1792
Integrated sequence
CGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCAT| |AAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTG
Host Sequence
Chromosome
chr7
Cytoband
p21.3
Reference genome
GRCh37.55
Start
10450034/10410407 (Hg38)
End
10450034/10410407 (Hg38)
Nearest miRNA
hsa-mir-339/Upstream/3343362; hsa-mir-10399/Downstream/7716813;
Nearest TSS
ENST00000635602/Upstream/449383; ENST00000422697/Downstream/292269;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/683821, chr7-CpG: 31/Downstream/369271
Nearby gene
NDUFA4
Upstream sequence
CAAAGCCTAGTTCTACCCCACTAATTCTATATTTAAAGCCTTTAGACATATTATATTTGAAATGTTGAAAAACTAACTCCAATTTTTTTTTTTTGTATGT
Downstream sequence
AAAGCAGTAGTTTAATATTCAAATATTTACATTTAGATGCAATAATATGAGCATTTAAGCCAAGTCAAATTTTCAAGGCCCTGATATACAATACTTTTAT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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