Basic Information
VIS ID
TVIS10018697
Fusion event
HBV-SUGCT integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1825
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
GRCh37.55
Start
40579945/40540346 (Hg38)
End
40579945/40540346 (Hg38)
Location type
Intron11
Target gene
SUGCT
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1183/Upstream/3620914; hsa-mir-10399/Downstream/2610549;
Nearest TSS
ENST00000635602/Upstream/265835; ENST00000460466/Downstream/6582;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/404927, chr7-CpG: 26/Downstream/1165234
Upstream sequence
gtttttatggtgattaaggagtgatcggagggggcttatatggtttgaattttcttctaaaggagggaagatctgggatttttttttttatcagcttgcc
Downstream sequence
agaaacaaaatagtaacagctggtatattgcagagccaaaattctaaacaggtctgcccaagtccaaaacccttatttctagttaccatgcCATGTGGCT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate