ANKIB1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018700
Fusion event
HBV-ANKIB1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1797
Integrated sequence
TTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATT| |GGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTT
Host Sequence
Chromosome
chr7
Cytoband
q21.2
Reference genome
GRCh37.55
Start
91957225/92327911 (Hg38)
End
91957225/92327911 (Hg38)
Location type
Intron5
Fragile sites / regions
FRA7E
Target gene
ANKIB1
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-335-5p ; hsa-mir-25-3p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-3185 ; hsa-mir-5582-3p
Nearest miRNA
hsa-mir-10525/Upstream/123813; hsa-mir-10399/Downstream/1154849;
Nearest TSS
ENST00000635602/Upstream/8489; ENST00000413588/Downstream/15227;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/81374, chr7-CpG: 44/Downstream/119474
Upstream sequence
AAACCTCAGAACTCCCTCCCAAGGAGGGGCATTTTTACTGATGGAACTAAGCTGATGTTTGCAACCATAAGAAGCAAAAGAGGAAGCTCAAGCAACTCAC
Downstream sequence
AATGTCTTATGCTTCTAAGAACATGAGTAACTTTTGAAACTTCTGAGTTTTTAAAAGGGCTATTTTTGTATTTGAATACAGAACAAAATGGTTTGTTAAA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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