VISDB Viral Integration Site DataBase

VIS ID

TVIS10018701

Fusion event

HBV-NRF1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1956

Integrated sequence

TCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTT| |TTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACC

Chromosome

chr7

Cytoband

q32.2

Reference genome

Start

End

129348471/129708631 (Hg38)

Location type

Intron5

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-320a ; hsa-mir-4772-5p ; hsa-mir-3127-5p ; hsa-mir-6823-5p ; hsa-mir-6798-5p ; hsa-mir-383-5p ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-377-3p ; hsa-mir-5579-3p ; hsa-mir-2115-5p ; hsa-mir-1277-5p ; hsa-mir-539-3p ; hsa-mir-485-3p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-5580-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-1249-5p ; hsa-mir-6797-5p ; hsa-mir-765 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4487 ; hsa-mir-4756-5p ; hsa-mir-3192-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-4779 ; hsa-mir-708-5p ; hsa-mir-3139 ; hsa-mir-28-5p ; hsa-mir-6083 ; hsa-mir-3912-5p ; hsa-mir-297 ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-6834-3p ; hsa-mir-380-3p ; hsa-mir-4495 ; hsa-mir-379-3p ; hsa-mir-411-3p ; hsa-mir-7108-5p ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-663b ; hsa-mir-7155-3p ; hsa-mir-3136-3p ; hsa-mir-33a-3p ; hsa-mir-3692-3p ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-183-3p ; hsa-mir-5701 ; hsa-mir-6776-5p ; hsa-mir-140-3p ; hsa-mir-944 ; hsa-mir-504-3p

Nearest miRNA

hsa-mir-10525/Upstream/1500688; hsa-mir-10399/Downstream/61752;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/96031, chr7-CpG: 53/Downstream/53749

Nearest cancer related gene

NRF1(TSG, No orient, 0)

Upstream sequence

ccagtgtggctgagtccggggctttgatgggcttagaatagtgaaatgcatgctgattcatttttgtgtatgcgaaaaaggttaaaacaaaggcaccact

Downstream sequence

atctataaataataatgattttatcagctcgcctcttatttctctcttatctaattgcatggattcctacttccagaacagtgttgaaAACACCCCGAGT