MLLT3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018702
Fusion event
HBV-MLLT3 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1817
Integrated sequence
TGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCAT| |GCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCT
Host Sequence
Chromosome
chr9
Cytoband
p21.3
Reference genome
GRCh37.55
Start
20529392/20529394 (Hg38)
End
20529392/20529394 (Hg38)
Location type
Intron9
Fragile sites / regions
FRA9C
Target gene
MLLT3
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-3924 ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-5692c ; hsa-mir-5692b
Nearest miRNA
hsa-mir-101-2/Upstream/27052; hsa-let-7a-1/Downstream/186711;
Nearest TSS
ENST00000422679/Upstream/117432; ENST00000604036/Downstream/92479;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/594565, chr9-CpG: 167/Downstream/91031
Nearest cancer related gene
MLLT3(OG, No orient, 0)
Upstream sequence
TATGCACTAAACTACATCTCTAttcttttttttttttttttttgagaaggcgtctcactctgtctcccaggctggagtgcaatggcatgatctcggctca
Downstream sequence
TTCCTCTGGAGTCCCTCTGAGGAGTGGTCTGTGATGGGACAGGGGCCCTGGAAGGGGAGGGAGGAAGGCAGGTGTGGCCGCCCCTTAGGAGGCAGGCAGA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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