Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018703
Fusion event
HBV-PCSK5 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
2913
Integrated sequence
GTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAG| |CCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGG
Host Sequence
Chromosome
chr9
Cytoband
q21.13
Reference genome
Start
End
78913283/76298367 (Hg38)
Location type
Intron27
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-101-2/Upstream/5488283; hsa-let-7a-1/Downstream/7671381;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/405631, chr9-CpG: 101/Downstream/95354
Upstream sequence
ATTTAAGTCCATGTTTATTGGATACAGTAATTATCACCCACTGTTGTATAAGCCTGATAACTAGGGCAAGGGAAGTTTGTGCTTTTGGCATATTTCTGAA
Downstream sequence
aaatgggcaatatcattaatgtttaaaaattggttaagttgtaacatagccacaaaacggatactatgacaccaccaaaaattatgATAATGATTaatgg
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.