Basic Information
VIS ID
TVIS10018705
Fusion event
HBV-chr11 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1789
Integrated sequence
GACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGG| |CATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGG
Host Sequence
Chromosome
chr11
Cytoband
p14.3
Reference genome
GRCh37.55
Start
25633294/25611748 (Hg38)
End
25633294/25611748 (Hg38)
Nearest miRNA
hsa-mir-210/Upstream/2192558; hsa-let-7a-2/Downstream/1903222;
Nearest TSS
ENST00000527297/Upstream/719983; ENST00000533942/Downstream/123022;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1114556, chr11-CpG: 29/Downstream/720242
Nearby gene
ANO3
Upstream sequence
AAGACATGGCAGCAGTGCAGAGGACCCTGATGGCTTTGGGCAGCTTGGCAGTGACCAAGAATGATGGGCACTACCGTGGAGATCCCAACTGGTTTATGAA
Downstream sequence
GTGACTGGGACCTTCAGTTTCAAGCCCTTCCGCAGAGTCACCAGCCCCCAGCATACCTTGCTGCAGAAAACGGTTGGGATAGAAGAGGGCCCTGGAACAA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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