Basic Information
VIS ID
TVIS10018706
Fusion event
HBV-chr11 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1631
Integrated sequence
CTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCC| |ACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGA
Host Sequence
Chromosome
chr11
Cytoband
q24.1
Reference genome
GRCh37.55
Start
121781934/121911226 (Hg38)
End
121781934/121911226 (Hg38)
Nearest miRNA
hsa-mir-10392/Upstream/2598214; hsa-let-7a-2/Downstream/188531;
Nearest TSS
ENST00000527297/Upstream/282390; ENST00000526777/Downstream/204989;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/458633, chr11-CpG: 113/Downstream/744344
Nearby gene
MIR100HG
Nearest cancer related gene
MIR100HG(OG, No orient)
Upstream sequence
ccaggatgcagaggttgcagtgagccaaaaAAAAAAAAAAAAGAATAATAATAGCTACAATACTTTATTAAGGTATATACAATATAAAAAGATGCAAATT
Downstream sequence
ACATGCTTAGCATGCACACTTTTACCACTTTTTTCGAGTGGAAAGTTTATTGGCAATATTAAATTTCACCCTAGATAGGATATGAGAATGTTTTGATAAA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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