Basic Information
VIS ID
TVIS10018716
Fusion event
HBV-chr18 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1821
Integrated sequence
TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
GRCh37.55
Start
64905145/67237908 (Hg38)
End
64905145/67237908 (Hg38)
Fragile sites / regions
FRA18C
Nearest miRNA
hsa-mir-1-2/Upstream/156222; hsa-mir-548av/Downstream/5615413;
Nearest TSS
ENST00000575820/Upstream/633770; ENST00000581951/Downstream/247058;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/1486504, chr18-CpG: 83/Downstream/278092
Nearby gene
MIR5011
Upstream sequence
gtgatccacccgcctcggcctcctaaattgctgggattacaggggtgagccaccgtgtccagccTCTTTTGTCTGGTTTCTAATTCTactagtgagtacc
Downstream sequence
gactacaataatcctcttgctcatatatttatttaagtgggttgacagacaatataccaatGttatttatataattaataaaatatGGTAGACAGGGACA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate