Basic Information
VIS ID
TVIS10018720
Fusion event
HBV-chrX integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1824
Integrated sequence
TTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTT| |TTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAG
Host Sequence
Chromosome
chrX
Cytoband
q13.3
Reference genome
GRCh37.55
Start
74228535/75008700 (Hg38)
End
74228535/75008700 (Hg38)
Nearest miRNA
hsa-let-7f-2/Upstream/721343; hsa-mir-105-1/Downstream/1910573;
Nearest TSS
ENST00000429181/Upstream/83215; ENST00000373373/Downstream/53927;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/83391, chrX-CpG: 31/Downstream/514230
Nearby gene
ABCB7
Upstream sequence
TTAGGTTTGCTTGAAATCTTGCAGATTGCCAGAACATCAGGCAAAAAATTCAAATATAAGTTTAAAAATATCATAACAAATTCAAAGACTGTATATTTAA
Downstream sequence
ttttctagttctttaagatgcattgtgagattgtttatttgaagattttcctctttatcagatgtaggcaccaatagttgtaaacttccctctgagtgct
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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