Basic Information
VIS ID
TVIS10018724
Fusion event
HBV-MIR2052HG integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1744
Integrated sequence
CAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTG| |GGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCAT
Host Sequence
Chromosome
chr8
Cytoband
q21.12
Reference genome
GRCh37.55
Start
75521162/74608927 (Hg38)
End
75521165/74608930 (Hg38)
Location type
Intron1
Target gene
MIR2052HG
Nearest miRNA
hsa-mir-124-1/Upstream/60310; hsa-mir-10400/Downstream/96763;
Nearest TSS
ENST00000518652/Upstream/9061; ENST00000521762/Downstream/24390;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/258118, chr8-CpG: 60/Downstream/375363
Upstream sequence
tcccagcactttgggaggccgaggcgggtggatcatgaggtcaggagatcgagaccatcctggctaacaaggtgaaaccccgtctctactaaaaatacaa
Downstream sequence
gttacagaacataataataaaaaccagagcagaaattaatgaatgagaaaacataaaagtaatagagaaaattaataaaaacaaaagaatttttaagatt
Target sequence
aat
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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