Basic Information
VIS ID
TVIS10018725
Fusion event
HBV-MIR2052HG integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1715
Integrated sequence
ACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAG| |ACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACC
Host Sequence
Chromosome
chr8
Cytoband
q21.12
Reference genome
GRCh37.55
Start
75525085/74612850 (Hg38)
End
75525087/74612852 (Hg38)
Location type
Intron1
Target gene
MIR2052HG
Nearest miRNA
hsa-mir-124-1/Upstream/64233; hsa-mir-10400/Downstream/92841;
Nearest TSS
ENST00000518652/Upstream/12984; ENST00000521762/Downstream/20468;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/262041, chr8-CpG: 60/Downstream/371441
Upstream sequence
gcctcccaaatagctgggattacagacatgcgccaccacacacagctaattttgtaactttagtagagacagggtttcaccatgttgcccaggcagtctc
Downstream sequence
TTCCCGAGAGATCCCATGATCCAGAGACAAAGGTGGCAGCTTTGGAGCAAGTGGAGAGCCAGAAAAGGATCCAGAACTGGAGTGGAAGGTGGGAAAGATC
Target sequence
AG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate