Basic Information
VIS ID
TVIS10018727
Fusion event
HBV-IGH integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1787
Integrated sequence
ACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTA| |GGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTT
Host Sequence
Chromosome
chr14
Cytoband
q32.33
Reference genome
GRCh37.55
Start
106493560/106037328 (Hg38)
End
106493571/106037339 (Hg38)
Location type
Intronic
Target gene
IGH
Nearest miRNA
hsa-mir-1185-1/Upstream/177775; hsa-mir-5195/Downstream/813546;
Nearest TSS
ENST00000550708/Upstream/11698; ENST00000605005/Downstream/1026;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/169267, chr14-CpG: 17/Downstream/176497
Nearby gene
ADAM6
Upstream sequence
agttttgttttttccagaatgtcatgcatttggaatcatgtagtaggtaccttttttatattggcttttttcatttaacaatgtatatttaggctttttt
Downstream sequence
TACGACATTTTTAGAAATTTATTTCTGCACTGTTACTGTGAGACACTCCGTGATGGGGACACATTCCATCTGttttattgttttataaaattattttatt
Target sequence
CACACCTACCC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate