Basic Information
VIS ID
TVIS10018729
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1369
End
1971
Integrated sequence
GTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTG
Host Sequence
Chromosome
chr1
Cytoband
p36.32
Reference genome
GRCh37.55
Start
5089790/5029730 (Hg38)
End
5089790/5029730 (Hg38)
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/1468940; hsa-mir-101-1/Downstream/832942;
Nearest TSS
ENST00000473358/Upstream/56349; ENST00000564261/Downstream/61169;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/257237, chr1-CpG: 43/Downstream/682266
Nearby gene
AJAP1
Nearest cancer related gene
AJAP1(TSG, No orient)
Upstream sequence
GTTTGAAACTTTATTAACACTCCTGAAGTTCTTTCTTTTTGCAGAGGCCTCTGATAGAAGATGCAGTTTCCCTAAACAGCCAGCTTCTGTTACCTTGGCA
Downstream sequence
AAAGTATTTTAAATGGGGAAAAAGCCATTATTTTTTGGTTGTGGGTTTTACACTGTCAGGTAAACAAAAATGTACAAGTAGAGAAGAAAGATGAATGCTT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate