Basic Information
VIS ID
TVIS10018733
Fusion event
HBV-LOC107986445 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1825
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chr5
Cytoband
q23.2
Reference genome
GRCh37.55
Start
121455132/122119437 (Hg38)
End
121455132/122119437 (Hg38)
Location type
Intronic
Target gene
LOC107986445
Nearest miRNA
hsa-mir-10397/Upstream/2964721; hsa-mir-103a-1/Downstream/6978251;
Nearest TSS
ENST00000502646/Upstream/41077; ENST00000505843/Downstream/10076;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/41043, chr5-CpG: 92/Downstream/192318
Nearby gene
ZNF474
Upstream sequence
CTTTCTTTCTGCTGACATGTATAACATAAAATTAGTTCACAAAGACATGGAAAATATACTTTCTTTTGCAAAGGTGGGCAATTATTTTAAACATTGCAAA
Downstream sequence
GTTGAGACTTTAACCACGTGATTTTGGAGAGGTTTCTTGTTTTTATAATCTTGAGGCTTAAGAGAACCATCTGACTCAGGGGAATTCAAAGGAAAAATAT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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