Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018737
Fusion event
HBV-ZNF251 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1717
Integrated sequence
CACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGAC| |TGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCAT
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
End
145956923/144731538 (Hg38)
Location type
Intron1
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-1233-5p ; hsa-mir-1298-3p ; hsa-mir-185-5p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3165 ; hsa-mir-4306 ; hsa-mir-452-3p ; hsa-mir-4644 ; hsa-mir-4667-5p ; hsa-mir-4700-5p ; hsa-mir-5192 ; hsa-mir-541-3p ; hsa-mir-6134 ; hsa-mir-637 ; hsa-mir-654-5p ; hsa-mir-6731-5p ; hsa-mir-6751-5p ; hsa-mir-6752-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6778-5p ; hsa-mir-6788-5p ; hsa-mir-6803-5p ; hsa-mir-6835-5p ; hsa-mir-6842-5p ; hsa-mir-6878-5p ; hsa-mir-6880-5p ; hsa-mir-7110-5p ; hsa-mir-7155-5p ; hsa-mir-8071 ; hsa-mir-8085 ; hsa-mir-8089 ; hsa-mir-92a-2-5p
Nearest miRNA
hsa-mir-10400/Upstream/268999; hsa-mir-6850/Downstream/60393;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/934, chr8-CpG: 72/Downstream/23609
Upstream sequence
AAGTGGCAGggaaaaggcaaaactatagacacagtaaaagattagtggttgccaggtgttggcagggtgctggggggtgggggaatcaatgaattggtca
Downstream sequence
tatttaaaggaagcgtcctgTTAGTGCTGCTTCTTTGTTATTTTATGTATGTTATCTATGCAttttgagacagagtcttgctctattgcccaggctggag
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.