Basic Information
VIS ID
TVIS10018739
Fusion event
HBV-chr10 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1795
Integrated sequence
CCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAA| |TTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCT
Host Sequence
Chromosome
chr10
Cytoband
q22.1
Reference genome
GRCh37.55
Start
72909538/71149781 (Hg38)
End
72909538/71149781 (Hg38)
Nearest miRNA
hsa-mir-1265/Upstream/3746371; hsa-mir-107/Downstream/640966;
Nearest TSS
ENST00000439456/Upstream/210648; ENST00000335350/Downstream/62789;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/230968, chr10-CpG: 161/Downstream/62537
Nearby gene
UNC5B
Nearest cancer related gene
UNC5B(TSG, No orient)
Upstream sequence
TGAGATGGAGTAAAGCCATCATTTTtaacagcaaacattcattgaagattcactctatgagcagtgcagtgctagctattttacgtgtattatctcagtc
Downstream sequence
aagcccagcttgtaattctcattaaccctgcgggggcagcttcaTTCCCAGGAATGATTCCCAAAAGCACATTGCAGATCTGAGTCACCAAAAACTATCA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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