Basic Information
VIS ID
TVIS10018743
Fusion event
HBV-chr16 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1794
Integrated sequence
ACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAA| |ATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGC
Host Sequence
Chromosome
chr16
Cytoband
q12.2
Reference genome
GRCh37.55
Start
53541029/53507117 (Hg38)
End
53541029/53507117 (Hg38)
Nearest miRNA
hsa-mir-1225/Upstream/2764740; hsa-mir-11401/Downstream/2738403;
Nearest TSS
ENST00000527434/Upstream/2706; ENST00000570395/Downstream/131257;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/3344, chr16-CpG: 51/Downstream/196588
Nearby gene
AKTIP
Nearest cancer related gene
AKTIP(OG, No orient)
Upstream sequence
ttttcctcttccttttagttcttctCTTTAAATGCCTTCTCACTCTGCACGGGGTCTAGACTTGACTTCTCCTTTGGCTCACTTCTTGCCTTTTGTTTCA
Downstream sequence
ACTATTAAAGGCCTTCACAGAAAGAAGGAAAGGATAAAATGTTGAAGGTTGTTAAAATACATATGTTTCATACACAGGCACACATATAAGCCGATGTTTT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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