Basic Information
VIS ID
TVIS10018746
Fusion event
HBV-chr10 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1792
Integrated sequence
CGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCAT| |AAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTG
Host Sequence
Chromosome
chr10
Cytoband
q23.2
Reference genome
GRCh37.55
Start
88340965/86581208 (Hg38)
End
88340969/86581212 (Hg38)
Fragile sites / regions
FRA10D
Nearest miRNA
hsa-mir-1265/Upstream/316420; hsa-mir-107/Downstream/922669;
Nearest TSS
ENST00000439456/Upstream/59263; ENST00000372071/Downstream/73345;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/44346, chr10-CpG: 51/Downstream/50777
Nearby gene
OPN4
Upstream sequence
ccatgtacatctattatgcatcaatttaaaaaaaaaaaAAAGAAAACAGGTCAGACAACCCTCCTGCTTAAAACTCTCCAATGGTtgaaaacgttctaca
Downstream sequence
tctggcctgttttgaagaagagagaatgctctcaggcaattcgatgcaagttctggcatttggaagtcaagccagcaagcaatgaaatggtaaaggttaa
Target sequence
cact
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate