VISDB Viral Integration Site DataBase

VIS ID

TVIS10018748

Fusion event

HBV-HSP90AA1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1279

End

1378

Integrated sequence

ACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGG

Chromosome

chr14

Cytoband

q32.31

Reference genome

Start

End

102547895/102081558 (Hg38)

Location type

Exon1

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-16-5p ; hsa-mir-1226-3p ; hsa-mir-760 ; hsa-mir-425-5p ; hsa-mir-421 ; hsa-mir-501-5p ; hsa-mir-484 ; hsa-mir-324-3p ; hsa-mir-378a-3p ; hsa-mir-30e-5p ; hsa-mir-186-5p ; hsa-mir-185-5p ; hsa-mir-222-3p ; hsa-mir-204-5p ; hsa-mir-183-5p ; hsa-mir-10a-5p ; hsa-mir-30c-5p ; hsa-mir-25-3p ; hsa-mir-17-5p ; hsa-let-7b-5p ; hsa-mir-3943 ; hsa-mir-1277-5p ; hsa-mir-4703-3p ; hsa-mir-4677-3p ; hsa-mir-4679 ; hsa-mir-889-3p ; hsa-mir-1323 ; hsa-mir-34c-5p ; hsa-mir-371a-5p ; hsa-mir-3674 ; hsa-mir-374a-3p ; hsa-mir-4732-5p ; hsa-mir-6832-5p ; hsa-mir-219a-2-3p ; hsa-mir-4257 ; hsa-mir-6847-5p ; hsa-mir-2115-3p ; hsa-mir-1278 ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-4724-5p ; hsa-mir-361-5p ; hsa-mir-499b-5p ; hsa-mir-500b-5p ; hsa-mir-362-5p ; hsa-mir-656-3p ; hsa-mir-224-5p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-3133 ; hsa-mir-495-3p ; hsa-mir-5688 ; hsa-mir-139-5p ; hsa-mir-6798-3p ; hsa-mir-582-5p ; hsa-mir-101-3p ; hsa-mir-550a-3p ; hsa-mir-200c-5p ; hsa-mir-600 ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-497-3p ; hsa-mir-5590-5p ; hsa-mir-6826-3p ; hsa-mir-6755-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-141-5p ; hsa-mir-1244 ; hsa-mir-548l ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-23a-3p

Nearest miRNA

hsa-mir-1185-1/Upstream/521013; hsa-mir-12121/Downstream/458086;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/65359, chr14-CpG: 157/Downstream/4826

Upstream sequence

ATCCTTCTAAACATGGTTGGGTTCAATGATCATGAAGAGAAGTGAACAGATTCACCAGACGTGGAGGAGACAAAATAAATAGATTTGTTGCTTCTTTGCC

Downstream sequence

CTTAGTAGACAGAAATCTTATCTTCCCCTTAAAGTAGTTGTCATGCCATACAGACTTTTTAATATTAACAAAAATAAAGAAAAACATCCTTGAAAATATA

Target sequence

AAAGTTAACATCATGTTACATACGTCTTACAGTGCACGTTACCCCAATCTGTGAAAATAAACCAACATGAAACTCAAAAAGCATTACTAGCTCTGCTTTAGTGCCTAAGGTATCACAGCATCA