Basic Information
VIS ID
TVIS10018749
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2971
Integrated sequence
GCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTG| |GCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTA
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
GRCh37.55
Start
37014070/36548469 (Hg38)
End
37014070/36548469 (Hg38)
Nearest miRNA
hsa-mir-12136/Upstream/1878775; hsa-mir-101-1/Downstream/613094;
Nearest TSS
ENST00000473358/Upstream/65191; ENST00000641463/Downstream/155484;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/83939, chr1-CpG: 233/Downstream/484307
Nearby gene
CSF3R
Nearest cancer related gene
CSF3R(OG, No orient)
Upstream sequence
AACATGATGGCATGATGGGTGACAGAGCGAGACTATGTCTgaaagaaggaaagagagaaggaaagcaagaaagcaagaaagcaagcaagcaagcaagaaa
Downstream sequence
TCTCCAAGACAATGTTGTTATAATATCTGATACTTATATCTCTGATTTTACATACATCTGTATAATGTGCATAATATAAAATAGTCTCTAAATTTGCATT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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