PPP2R2C _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018753
Fusion event
HBV-PPP2R2C integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1140
Integrated sequence
GGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGA| |ACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCG
Host Sequence
Chromosome
chr4
Cytoband
p16.1
Reference genome
GRCh37.55
Start
6486255/6484528 (Hg38)
End
6486255/6484528 (Hg38)
Location type
Intron8
Fragile sites / regions
FRA4A
Target gene
PPP2R2C
miRNAs that regulate target gene
hsa-mir-142-3p
Nearest miRNA
hsa-mir-378d-1/Upstream/561200; hsa-mir-12113/Downstream/825922;
Nearest TSS
ENST00000502981/Upstream/12082; ENST00000504960/Downstream/39019;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/11721, chr4-CpG: 138/Downstream/78496
Nearest cancer related gene
PPP2R2C(TSG, No orient, 0)
Upstream sequence
gttaactccaatcaactgatagtggctgtcctgcagctttgtgctgtgagtgtttctaagactgagcataagctcagagagaaagagtgcagtgatcaga
Downstream sequence
gttcagatattgtttacactgtgttgaatttcagatcaatttggggggaactgccatcttaacaatattgagtcttccaatccactcccatagtatatct
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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