PAPSS1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018754
Fusion event
HBV-PAPSS1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1407
Integrated sequence
AGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCC| |TGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCC
Host Sequence
Chromosome
chr4
Cytoband
q25
Reference genome
GRCh37.55
Start
108639818/107718662 (Hg38)
End
108639818/107718662 (Hg38)
Location type
Intron11
Target gene
PAPSS1
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-100-5p
Nearest miRNA
hsa-mir-12113/Upstream/6388248; hsa-mir-1243/Downstream/1770036;
Nearest TSS
ENST00000502981/Upstream/24364; ENST00000515332/Downstream/1361;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/682374, chr4-CpG: 109/Downstream/1027
Upstream sequence
atatgtatacatgcgccatgttggtgtgctgcacccattaactcgtcatttacattaggtatatctcctaatgctatccctcccccctcccccgaccacc
Downstream sequence
CTAGCACAAGTCTCTACATAGAATACGCACCATGTGGCAAATGTTAATAAATAAATGAGTACATAAATGGACAATGTAACAGAAATCATCTGTAAATACC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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