PAPSS1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018755
Fusion event
HBV-PAPSS1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
458
Integrated sequence
CTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCA| |AGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTAT
Host Sequence
Chromosome
chr4
Cytoband
q25
Reference genome
GRCh37.55
Start
108640366/107719210 (Hg38)
End
108640366/107719210 (Hg38)
Location type
Intron11
Target gene
PAPSS1
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-100-5p
Nearest miRNA
hsa-mir-12113/Upstream/6388796; hsa-mir-1243/Downstream/1769488;
Nearest TSS
ENST00000502981/Upstream/24912; ENST00000515332/Downstream/813;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/682922, chr4-CpG: 109/Downstream/479
Upstream sequence
TTGATCTTCATTTATGCCTTGCTTTTTGTCAACATTAGAAGTTTCAATAAATGCTGGCAACATTTCAGATGACATTATTTGGTGCCTCTGAAAAACAACT
Downstream sequence
AGGGCAAGTAACGTTTTGGGAGACATTGCATTTAAACCTTATTATTCCATTGGACTGTGAAATAACGTTTCCGTCTAAACTTAAACCAGTGCCTTTCCAG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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