VISDB Viral Integration Site DataBase

VIS ID

TVIS10018757

Fusion event

HBV-CANX integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

402

End

1299

Integrated sequence

TTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCA

Chromosome

chr5

Cytoband

q35.3

Reference genome

Start

End

179155589/179728588 (Hg38)

Location type

Intron14

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-935 ; hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-mir-342-3p ; hsa-mir-30e-5p ; hsa-mir-320a ; hsa-mir-185-5p ; hsa-mir-222-3p ; hsa-mir-196a-5p ; hsa-mir-18a-5p ; hsa-mir-17-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-187-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-503-5p ; hsa-mir-605-3p ; hsa-mir-548c-3p ; hsa-mir-646 ; hsa-mir-1283 ; hsa-mir-1277-5p ; hsa-mir-3613-3p ; hsa-mir-4493 ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-5690 ; hsa-mir-6126 ; hsa-mir-6838-5p ; hsa-mir-3190-3p ; hsa-mir-3185 ; hsa-mir-136-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-505-3p ; hsa-mir-3681-3p ; hsa-mir-8485 ; hsa-mir-570-3p ; hsa-mir-323a-3p ; hsa-mir-6132 ; hsa-mir-6836-5p ; hsa-mir-539-3p ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-431-5p ; hsa-mir-8075 ; hsa-mir-219b-5p ; hsa-mir-8069 ; hsa-mir-4670-3p ; hsa-mir-4635 ; hsa-mir-6893-3p ; hsa-mir-93-3p ; hsa-mir-370-3p ; hsa-mir-596 ; hsa-mir-6077 ; hsa-mir-7-5p ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-6825-5p ; hsa-mir-7106-5p ; hsa-mir-6797-5p ; hsa-mir-6878-5p ; hsa-mir-1249-5p ; hsa-mir-765 ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-1253 ; hsa-mir-6760-5p ; hsa-mir-4779 ; hsa-mir-655-3p ; hsa-mir-374c-5p ; hsa-mir-7161-3p ; hsa-mir-3156-5p ; hsa-mir-106a-3p ; hsa-mir-1252-5p ; hsa-mir-1299 ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-3612 ; hsa-mir-4695-5p ; hsa-mir-4782-5p ; hsa-mir-5093 ; hsa-mir-516b-5p ; hsa-mir-5706 ; hsa-mir-6128 ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6804-5p ; hsa-mir-6891-5p ; hsa-mir-875-3p ; hsa-mir-95-3p

Nearest miRNA

hsa-mir-10397/Upstream/3099088; hsa-mir-1229/Downstream/69690;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/29249, chr5-CpG: 124/Downstream/3878

Upstream sequence

ATTTCTGCAGTGGGTTTCTAAGTCCTCTGCACAATTATATGCTGAGCCTTTCTTGAAGGTCCACTTGGGGAGCTTCACCTTTCTGGGCTCTCCTTTTCTG

Downstream sequence

AGGAGGATGAAATTTTGAACAGATCACCAAGAAACAGAAAGCCACGAAGAGAGTGAAACAATCTTAAGAGCTTGATCTGTGATTTCTTCTCCCTCCTCCC