VISDB Viral Integration Site DataBase

VIS ID

TVIS10018758

Fusion event

HBV-HSP90AB1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

491

End

1518

Integrated sequence

ATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGAT

Chromosome

chr6

Cytoband

p21.1

Reference genome

Start

End

44217320/44249583 (Hg38)

Location type

Exon3

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-877-3p ; hsa-mir-455-3p ; hsa-mir-296-3p ; hsa-mir-93-3p ; hsa-mir-615-3p ; hsa-mir-501-5p ; hsa-mir-181d-5p ; hsa-mir-484 ; hsa-mir-320a ; hsa-mir-186-5p ; hsa-mir-15b-5p ; hsa-mir-92a-3p ; hsa-mir-6832-5p ; hsa-mir-185-3p ; hsa-mir-4489 ; hsa-mir-4283 ; hsa-mir-6716-5p ; hsa-mir-6876-3p ; hsa-mir-626 ; hsa-mir-335-5p ; hsa-mir-3675-5p ; hsa-mir-6873-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-5003-5p ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-1226-3p ; hsa-mir-1233-5p ; hsa-mir-1238-5p ; hsa-mir-1302 ; hsa-mir-1343-5p ; hsa-mir-17-3p ; hsa-mir-1909-3p ; hsa-mir-194-3p ; hsa-mir-214-3p ; hsa-mir-3117-5p ; hsa-mir-3144-5p ; hsa-mir-3191-3p ; hsa-mir-3619-5p ; hsa-mir-4298 ; hsa-mir-4300 ; hsa-mir-4530 ; hsa-mir-4641 ; hsa-mir-4648 ; hsa-mir-4652-5p ; hsa-mir-4688 ; hsa-mir-4716-3p ; hsa-mir-4723-5p ; hsa-mir-485-5p ; hsa-mir-505-5p ; hsa-mir-5591-5p ; hsa-mir-5698 ; hsa-mir-6090 ; hsa-mir-634 ; hsa-mir-6499-3p ; hsa-mir-6510-5p ; hsa-mir-6722-3p ; hsa-mir-6726-5p ; hsa-mir-6743-5p ; hsa-mir-6778-5p ; hsa-mir-6794-5p ; hsa-mir-6798-5p ; hsa-mir-6810-5p ; hsa-mir-6827-5p ; hsa-mir-6870-5p ; hsa-mir-6884-5p ; hsa-mir-7111-5p ; hsa-mir-761 ; hsa-mir-920 ; hsa-mir-939-5p

Nearest miRNA

hsa-mir-10398/Upstream/814963; hsa-mir-10524/Downstream/4623;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/1613, chr6-CpG: 84/Downstream/7378

Upstream sequence

cacgaaggtgccaatttgcagttttctcacttaatgcatcttggaaatcaAGATGTCAATATAATGAGTTTATGCATTTTCAGTAATGAACCTAGTCACT

Downstream sequence

GTATTGCAGTTCTGTAGGCATTCATACTTATCTGTGTTCTTTGGTTTTTTGCTTCTTTAAAACTTGTGATTGACTTTAAACTTGTTGGCAGGCTGGTGCA