VISDB Viral Integration Site DataBase

VIS ID

TVIS10018763

Fusion event

HBV-PTMS integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

284

End

558

Integrated sequence

GGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGC

Chromosome

chr12

Cytoband

p13.31

Reference genome

Start

End

6879384/6770218 (Hg38)

Location type

Exon4

Target gene

miRNAs that regulate target gene

hsa-mir-22-3p ; hsa-mir-193b-3p ; hsa-mir-155-5p ; hsa-mir-34a-5p ; hsa-mir-30a-5p ; hsa-mir-296-3p ; hsa-mir-423-3p ; hsa-mir-1249-5p ; hsa-mir-1286 ; hsa-mir-135a-3p ; hsa-mir-363-5p ; hsa-mir-3675-5p ; hsa-mir-4269 ; hsa-mir-4436a ; hsa-mir-4514 ; hsa-mir-4692 ; hsa-mir-4742-5p ; hsa-mir-4772-5p ; hsa-mir-486-3p ; hsa-mir-5000-3p ; hsa-mir-5191 ; hsa-mir-5197-5p ; hsa-mir-5586-3p ; hsa-mir-6515-5p ; hsa-mir-6715b-5p ; hsa-mir-6721-5p ; hsa-mir-6745 ; hsa-mir-6757-5p ; hsa-mir-6797-5p ; hsa-mir-6804-5p ; hsa-mir-6808-5p ; hsa-mir-6819-5p ; hsa-mir-6880-5p ; hsa-mir-6893-5p ; hsa-mir-759 ; hsa-mir-7847-3p ; hsa-mir-940

Nearest miRNA

hsa-mir-3649/Upstream/5109774; hsa-let-7i/Downstream/193481;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/2397, chr12-CpG: 36/Downstream/3471

Upstream sequence

caatgcttagctccattttacagatggggaaatggaaccttagagacggtgtcttaaccaagggtcacccggctgctggctggctgaccgagggcCAATA

Downstream sequence

GTTTGGGCTGGGTTGCTGGGCCTGAGGGGCTGTCAGGGATGCAGCCGGGCTGGGCGCCCTTTGGATTTGGACCCAGATCCCTGTGTGGCAGGGGTGGGGG

Target sequence

AGATGAGGAAGAAGAAGAAGAGGATGATGAAGGGCCCGCGCTGAAGAGAGCTGCCGAAGAGGAG