Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018767
Fusion event
HBV-MRPS15 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
457
Integrated sequence
ACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATC| |AAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTA
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
Start
End
36927828/36462227 (Hg38)
Location type
Intron6
Target gene
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-186-5p ; hsa-mir-4279 ; hsa-mir-6868-3p ; hsa-mir-6881-3p ; hsa-mir-6515-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-877-3p ; hsa-mir-4650-5p ; hsa-mir-1972 ; hsa-mir-10a-3p ; hsa-mir-7152-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-6818-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-5088-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-3142 ; hsa-mir-1245b-5p ; hsa-mir-4695-5p
Nearest miRNA
hsa-mir-12136/Upstream/1792469; hsa-mir-101-1/Downstream/699336;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/11440, chr1-CpG: 63/Downstream/1586
Upstream sequence
TAGTGTATAGACGTTTCAGTCTTTTTAATTGTTTTAACTTTTGCCTGTCAGAGCTTCATAGCAATAGTTAAAGGTTAACATGGAAATACTGGGTAAGAAA
Downstream sequence
CTGGCTCTTTTCACCCACTCTCCAACTCCAGAAGGGACATTCAGGGTCTCAAGCAAAGCACTGGATATCTCTCGGCTCAGTTTCTCCTTTGCAAACTCCG
Target sequence
CTGTCAAGTAAATATGGGGATAGAAAACACCCAGAGTCAACTCTCGCTGCCCACCCTCCCAGAC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.