VISDB Viral Integration Site DataBase

VIS ID

TVIS10018776

Fusion event

HBV-FN1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

488

Integrated sequence

GGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCC| |AGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGAC

Chromosome

chr2

Cytoband

q35

Reference genome

Start

End

216283963/215419240 (Hg38)

Location type

Intron34

Target gene

miRNAs that regulate target gene

hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-1-3p ; hsa-let-7g-5p ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-140-3p

Nearest miRNA

hsa-mir-10b/Upstream/1660875; hsa-mir-1244-1/Downstream/2481273;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/106625, chr2-CpG: 43/Downstream/16304

Upstream sequence

CTCGATATCCAGTGAGCTGAACATTGGGTGGTGTCCACTGGGCGCTCAGGCTTGTGGGTGTGACCTGAGTGAACTTCAGGTCAGTTGGTGCAGGAATAGC

Downstream sequence

CTTGGATAGGTCTGTAAAGGTTGGCAATGCCACTCCCCAATGCCACGGCCATAGCAGTAGCACTGGTATCTGACACCATGCACATACTTCTCCCATGAAT

Target sequence

TTTCATAGCCTTCTCTACCTTTTACTTGATAGAGGAAGAGAGAAAAATTATTTTAATCAAAAATTCAATTGATTATTAGATAATAACAAGAGAAAAGGGTGGGAAAGAGGGGAGACCCCCAACTTAGGCATGAGAGCATTAATAATCACTGCCCTGTTGTTATAACCCAATTGGCAGTTCTCAACTTGCAGTAATAGAGCTACTTA