FRAS1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018777
Fusion event
HBV-FRAS1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
461
Integrated sequence
GTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGG| |TATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCC
Host Sequence
Chromosome
chr4
Cytoband
q21.21
Reference genome
GRCh37.55
Start
79102889/78181735 (Hg38)
End
79102889/78181735 (Hg38)
Location type
Intron2
Target gene
FRAS1
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-12113/Upstream/1606109; hsa-mir-1243/Downstream/4571602;
Nearest TSS
ENST00000502981/Upstream/124131; ENST00000502446/Downstream/63496;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/122479, chr4-CpG: 34/Downstream/11
Upstream sequence
gggatgaagcccacttctgttacagaaggtcatctgttttactcaagtccactgatttaaatgttgatctcatccaaaaacaccttcacggaaacatcca
Downstream sequence
TCTTTCTTAAGCGCCACGGGCGGCTGCGTCTCCTCTTTCTTGTCAACCACGCCAACGCTGCGGGGCAGCGGGTTCTTGCGGTCTTTCTGGGACTCCTTGC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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