hsa-mir-4659a-3p _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018787
Fusion event
HBV-chr14 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2063
Integrated sequence
CTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGC| |ACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGT
Host Sequence
Chromosome
chr14
Cytoband
q13.2
Reference genome
GRCh37.55
Start
36074916/35605710 (Hg38)
End
36074916/35605710 (Hg38)
Location type
Intron
Target gene
RALGAPA1 ; RALGAPA1P1
miRNAs that regulate target gene
hsa-mir-17-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-6868-3p ; hsa-mir-2355-5p ; hsa-mir-361-5p ; hsa-mir-627-3p ; hsa-mir-4778-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-2115-3p ; hsa-mir-3074-3p ; hsa-mir-4282
Nearest miRNA
hsa-mir-208a/Upstream/4590968; hsa-mir-1185-1/Downstream/1346599;
Nearest TSS
ENST00000550708/Upstream/32850; ENST00000547420/Downstream/21566;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/69903, chr14-CpG: 62/Downstream/202862
Upstream sequence
CTCCCTCTGCATTTCTGACTTTGCTGTGCCGGCAGCCTGGAGCctcccaggtccctgctgtcatcttttctagccactacagtctctgtctttcctttca
Downstream sequence
TATAAAACAAAAGATTACACCATTAATTTAATCACTATTTTATCTACTCATTCATCCAACAATTAAGTTCTATGTACAAAGTATGTAGCAATAAAAAGAT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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