Basic Information
VIS ID
TVIS10018789
Fusion event
HBV-chr18 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1671
End
1890
Integrated sequence
ACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGT
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
GRCh37.55
Start
26408018/28828054 (Hg38)
End
26408018/28828054 (Hg38)
Nearest miRNA
hsa-mir-1-2/Upstream/2236519; hsa-mir-122/Downstream/1470856;
Nearest TSS
ENST00000575820/Upstream/42986; ENST00000584482/Downstream/533909;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/649843, chr18-CpG: 128/Downstream/2213469
Nearby gene
CDH2
Upstream sequence
AAAGGCTAAATTACCTTTATTCAACTTTTTTCCCCTAATAAAACAGCAATGCCTTGCTAGAAGACAATTTATTTAATTTTTAATGTGTTCTCTTCCTACC
Downstream sequence
caaggaaattgaggctcagTGTTTGTGACATTTGAATTCACTAAGTGCACCACAGATGAATAGACAAGTCTGTTAAATTCTAAAATCTAAATTTTATCAT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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