Basic Information
VIS ID
TVIS10018792
Fusion event
HBV-chr10 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
3065
Integrated sequence
CACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGC| |ATACTACAAACTTTGCCAGCAAATCCGCCTCCTGCCTCCACCAATCGCCAGTCAGGAAGGCAGCCTACCCCGCTGTCTCCACCTTTGAGAAACACTCATC
Host Sequence
Chromosome
chr10
Cytoband
q26.2
Reference genome
GRCh37.55
Start
130258945/128460681 (Hg38)
End
130258945/128460681 (Hg38)
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/2640859; hsa-mir-202/Downstream/1382618;
Nearest TSS
ENST00000439456/Upstream/140467; ENST00000446589/Downstream/452198;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/173520, chr10-CpG: 22/Downstream/39914
Nearby gene
LINC01163
Upstream sequence
gcactcgtgtgtgtgtgtgtgtgtgcacatgcatgtgtgcatgtttaggtctatgcgattttctctcttgtgtagattcatgtgattaccaccacagtca
Downstream sequence
tccacaataacctatgaaataggtactatttctagcaccctttttcaTGTAATGTGGGTCCTTATAGTAAATGAAAATATGTAATAATACATTAAAACAT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate