EHBP1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018796
Fusion event
HBV-EHBP1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1797
Integrated sequence
TTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATT| |GGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTT
Host Sequence
Chromosome
chr2
Cytoband
p15
Reference genome
GRCh37.55
Start
63039339/62812204 (Hg38)
End
63039339/62812204 (Hg38)
Location type
Intron5
Fragile sites / regions
FRA2S
Target gene
EHBP1
miRNAs that regulate target gene
hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1301/Upstream/606287; hsa-mir-10b/Downstream/1528543;
Nearest TSS
ENST00000437798/Upstream/105012; ENST00000462441/Downstream/46234;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/105986, chr2-CpG: 24/Downstream/232788
Upstream sequence
GTCTCTTTTGTGGCTAATAATCCTGCTTTGGGAGTAGATCTGATTTCTGAAAATCATTTTGTATCCAAAATAATGTAAGCCTGTAAAGGAAAAACCTGAT
Downstream sequence
ttaggctctagaactgtgagccaaataagtttcttttcttaataaattacccactctctgatactcttgttacagcagcaaaaaaaaatggactaagaca
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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