Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018800
Fusion event
HBV-MAML3 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1750
Integrated sequence
CTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAG| |GAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTG
Host Sequence
Chromosome
chr4
Cytoband
q31.1
Reference genome
End
140843030/139921876 (Hg38)
Location type
Intron5
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-3682-3p ; hsa-mir-4424 ; hsa-mir-4679 ; hsa-mir-1273g-3p ; hsa-mir-1272 ; hsa-mir-1255b-2-3p ; hsa-mir-4477b ; hsa-mir-5684 ; hsa-mir-651-3p ; hsa-mir-548c-3p ; hsa-mir-452-3p ; hsa-mir-576-3p ; hsa-mir-539-3p ; hsa-mir-485-3p ; hsa-mir-101-3p ; hsa-mir-144-3p ; hsa-mir-499a-3p ; hsa-mir-499b-3p ; hsa-mir-505-3p ; hsa-mir-5696 ; hsa-mir-579-3p ; hsa-mir-664b-3p
Nearest miRNA
hsa-mir-12113/Upstream/14414569; hsa-mir-1305/Downstream/3421584;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/61597, chr4-CpG: 20/Downstream/228493
Upstream sequence
GTTTGAGGGCTATAATTTTTCTATTTACTTCTGGCCTGTTTCTTGCCCCTGGAGAAGGAAATAACAAAGCTCGTTACCTTATGCCCATTTATACATATGT
Downstream sequence
AGTCCTCTGAAACCCTATGCCAATCCAATAAAGGTATCAGCAGTTCAGTGTGGGGAGGCAATTACTATATGGTCCCAAGTGTGCCTTCTAAGCTCTAGGA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.