Basic Information
VIS ID
TVIS10018802
Fusion event
HBV-chr5 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1684
End
1783
Integrated sequence
TCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCT
Host Sequence
Chromosome
chr5
Cytoband
p14.1
Reference genome
GRCh37.55
Start
26707514/26707405 (Hg38)
End
26707514/26707405 (Hg38)
Fragile sites / regions
FRA5E
Nearest miRNA
hsa-mir-10397/Upstream/9551413; hsa-mir-103a-1/Downstream/5228697;
Nearest TSS
ENST00000502646/Upstream/307586; ENST00000514255/Downstream/42592;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/37610, chr5-CpG: 76/Downstream/2101888
Nearby gene
CDH9
Upstream sequence
TGTCCATTGTAACCATACGCAGATTTTGCTCTATTCCATTGTTCAACTCATTCTGCAATTAAGCATAACTGTAGAGGAAAAATCTAGTTTTCCATACTCA
Downstream sequence
gtgagtccattatacctctttttcttttaaattacccagtcttgggtatgtctttattagcagcatgaggacagaccaataGAgtaaattggtacaggga
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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