NRG1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018810
Fusion event
HBV-NRG1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1773
Integrated sequence
TCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGT| |ACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCT
Host Sequence
Chromosome
chr8
Cytoband
p12
Reference genome
GRCh37.55
Start
32175575/32318059 (Hg38)
End
32175575/32318059 (Hg38)
Location type
Intron1
Target gene
NRG1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-125a-3p
Nearest miRNA
hsa-mir-124-1/Upstream/2360711; hsa-mir-10400/Downstream/8952989;
Nearest TSS
ENST00000518652/Upstream/97017; ENST00000520502/Downstream/230151;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/677229, chr8-CpG: 169/Downstream/229830
Upstream sequence
ttcctcttaaagcccatttttattatattgggcccacttagagagtaaagaataataggccagccgcagtggctcacgcctgtaatcccagcactttggg
Downstream sequence
AGGTAGGAAATAATCAGATTCTAAAGTTCTCACAAGGTTTGGTATTTTGAAGTATTTGGCAGAAGGCAAGGGTATGGAAAACTTTAAGAAATTGTAAGCT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate