Basic Information
VIS ID
TVIS10018811
Fusion event
HBV-MIR1268A integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1824
Integrated sequence
TTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTT| |TTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAG
Host Sequence
Chromosome
chr8
Cytoband
p11.23
Reference genome
GRCh37.55
Start
37252228/37394710 (Hg38)
End
37252228/37394710 (Hg38)
Location type
Intron2
Target gene
MIR1268A
Nearest miRNA
hsa-mir-124-1/Upstream/7437362; hsa-mir-10400/Downstream/3876338;
Nearest TSS
ENST00000518652/Upstream/325292; ENST00000517897/Downstream/12014;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/2158117, chr8-CpG: 351/Downstream/299716
Upstream sequence
TCAATGTACATTATTAAAAGATATAATACAGGTTCATGTTCTACGCAGAACTAAACTTTTTCAAAAAAAGTATTTTATCAATAACTAGATTACATGTGGA
Downstream sequence
AATTGAGGTAGAATAACAGCCAGTAGACTGGAAAATGAATGAGAGCACTCAAGATGCTGCGGGCAACTGAAGAAGTTAGCTCTGCAGAGGAATGAAGACA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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