Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018813
Fusion event
HBV-TCF7L2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1584
End
1756
Integrated sequence
ACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTA
Host Sequence
Chromosome
chr10
Cytoband
q25.2
Reference genome
End
114791948/113032189 (Hg38)
Location type
Intron4
Target gene
miRNAs that regulate target gene
hsa-mir-324-5p ; hsa-mir-148b-3p ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-513a-3p ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-3613-3p ; hsa-mir-4435 ; hsa-mir-1298-5p ; hsa-mir-539-3p ; hsa-mir-485-3p ; hsa-mir-539-5p ; hsa-mir-3190-5p ; hsa-mir-4793-3p ; hsa-mir-3919 ; hsa-mir-892b ; hsa-mir-6807-3p ; hsa-mir-217 ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418 ; hsa-mir-1-5p ; hsa-mir-193a-3p ; hsa-mir-193b-3p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-651-5p ; hsa-mir-3117-3p ; hsa-mir-891b ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-5193 ; hsa-mir-8083 ; hsa-mir-4759 ; hsa-mir-3169 ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-20a-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-526b-3p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-3666 ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-155-3p ; hsa-mir-32-3p ; hsa-mir-1305 ; hsa-mir-421 ; hsa-mir-7159-5p ; hsa-mir-8485 ; hsa-mir-505-3p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-623 ; hsa-mir-6832-3p ; hsa-mir-3938 ; hsa-mir-4717-5p ; hsa-mir-4753-5p ; hsa-mir-6768-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-26a-1-3p
Nearest miRNA
hsa-mir-107/Upstream/397935; hsa-mir-202/Downstream/745804;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/79404, chr10-CpG: 30/Downstream/94509
Nearest cancer related gene
TCF7L2(TSG, No orient, 0)
Upstream sequence
caccacgcctggctaatttttgtatttttagtagagatggggcttcaccatgctggccaggcagctctcaaaatcctgaccttaagtcatctgccagcct
Downstream sequence
agatacaaaagagttcctcgtgatgtcctttaacagccatagctacttccttgctccccttcctaatctatagaaatcactgaattcttctttatctcta
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.