Basic Information
VIS ID
TVIS10018821
Fusion event
HBV-chr16 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1095
End
1790
Integrated sequence
CTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCC
Host Sequence
Chromosome
chr16
Cytoband
q22.2
Reference genome
GRCh37.55
Start
71843443/71809540 (Hg38)
End
71843443/71809540 (Hg38)
Nearest miRNA
hsa-mir-1225/Upstream/1779118; hsa-mir-11401/Downstream/5059396;
Nearest TSS
ENST00000527434/Upstream/339; ENST00000565676/Downstream/36451;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/342, chr16-CpG: 53/Downstream/36320
Nearby gene
ATXN1L
Upstream sequence
agggtaccaaaatcattcagtggagaaagaacaatgttttcaacaactgatgctaggacaactgaatatctggaccaaaaaagataaaaatggactgtca
Downstream sequence
GTACCGCGGTGCTTGCACTGCTcaagtcacttaaactctccagggattcaatttcctcatatgtagaaagaagacttggactcatgttagctgaaaccct
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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