Basic Information
VIS ID
TVIS10018823
Fusion event
HBV-chr17 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1821
Integrated sequence
TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
GRCh37.55
Start
3607131/3703837 (Hg38)
End
3607131/3703837 (Hg38)
Nearest miRNA
hsa-mir-1253/Upstream/955655; hsa-mir-10226/Downstream/1265865;
Nearest TSS
ENST00000595228/Upstream/7433; ENST00000571741/Downstream/14542;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/7580, chr17-CpG: 111/Downstream/19793
Nearby gene
ITGAE
Upstream sequence
ttggtttttctggtgaccagcccctatcctgaagttccctgggagtcgtcagccgcctcattaggatacaaaagatgctcttatcactgtggagattcca
Downstream sequence
cgcctgtaatcccagcactttgggaggccgaggtgggtggatcacctgaggtcaggagttcgagaccagcctgaccaacatggagaaaccccatctctac
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate