Basic Information
VIS ID
TVIS10018824
Fusion event
HBV-EFCAB13 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1815
Integrated sequence
ACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACC
Host Sequence
Chromosome
chr17
Cytoband
q21.32
Reference genome
GRCh37.55
Start
45496102/47418736 (Hg38)
End
45496102/47418736 (Hg38)
Location type
Intron23
Target gene
EFCAB13
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1180/Upstream/445636; hsa-mir-10226/Downstream/614146;
Nearest TSS
ENST00000595228/Upstream/40920; ENST00000533573/Downstream/4790;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/94662, chr17-CpG: 120/Downstream/4678
Upstream sequence
gtccccaccccgattccatagctagatgtcatagttcttcagtctccttcaatttggaatagtccccctagcctttctccctaccttctgtgacattttt
Downstream sequence
atgacagtccatttttatcttttttgttccagatattcagttgtcctagcatcagttgttgaaaacattgttctttctccactgaatgattttggtaccc
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate