VISDB Viral Integration Site DataBase

VIS ID

TVIS10018826

Fusion event

HBV-MRO integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1717

Integrated sequence

CACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGAC| |TGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCAT

Chromosome

chr18

Cytoband

q21.2

Reference genome

Start

End

48325599/50799229 (Hg38)

Location type

Exon1

Target gene

miRNAs that regulate target gene

hsa-mir-2110 ; hsa-mir-491-5p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-3202 ; hsa-mir-3179 ; hsa-mir-203a-3p ; hsa-mir-6783-5p ; hsa-mir-3611 ; hsa-mir-3140-3p ; hsa-mir-7706 ; hsa-mir-4325 ; hsa-mir-7703 ; hsa-mir-616-3p ; hsa-mir-4537 ; hsa-mir-187-3p ; hsa-mir-4317 ; hsa-mir-6774-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4786-5p ; hsa-mir-383-3p ; hsa-mir-4761-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-548s ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-4684-5p ; hsa-mir-3926 ; hsa-mir-769-5p ; hsa-mir-3190-5p ; hsa-mir-6827-3p ; hsa-mir-340-3p ; hsa-mir-6849-3p ; hsa-mir-6771-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-210-5p ; hsa-mir-4749-3p ; hsa-mir-2276-3p ; hsa-mir-1248 ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-4693-3p ; hsa-mir-4461 ; hsa-mir-4279 ; hsa-mir-630 ; hsa-mir-570-5p ; hsa-mir-548ba ; hsa-mir-548ai ; hsa-mir-548ag ; hsa-mir-7109-3p ; hsa-mir-1273e ; hsa-mir-3689d ; hsa-mir-4459 ; hsa-mir-6134 ; hsa-mir-665 ; hsa-mir-6840-3p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-7847-3p ; hsa-mir-3157-5p ; hsa-mir-4691-3p ; hsa-mir-6787-3p

Nearest miRNA

hsa-mir-1-2/Upstream/672666; hsa-mir-122/Downstream/2437872;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/69240, chr18-CpG: 109/Downstream/79536

Upstream sequence

TGCTTGGGTGGATCTGTATGTGTGCATAAGTGTACATCTATGAGCTAAATTTTCACAGCCATTTGCCAAGATTAAGGAACAAAATAGGTGTCTAAAGATA

Downstream sequence

AATCCCAAGAGGCAAGCAGTGAGAAGAGGCATCCAGTGAGATAAAACAGGGGAACATGATGGCTCAGCAATGCACTCATACAGAACCATTTCCCTGCTGC