Basic Information
VIS ID
TVIS10018827
Fusion event
HBV-LOC105372310 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1807
Integrated sequence
CTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCA| |CCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGA
Host Sequence
Chromosome
chr19
Cytoband
p12
Reference genome
GRCh37.55
Start
20270604/20159795 (Hg38)
End
20270604/20159795 (Hg38)
Location type
Intronic
Target gene
LOC105372310
Nearest miRNA
hsa-mir-10395/Upstream/724637; hsa-let-7e/Downstream/239477;
Nearest TSS
ENST00000633603/Upstream/9247; ENST00000597083/Downstream/7433;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/107497, chr19-CpG: 19/Downstream/922563
Nearby gene
ZNF486
Upstream sequence
GATTGCGGGCGTGGGTTCCTTGCCGCTGTCTGGGGTAGAGGAGAAGATGTTCAGCCTCCTCAAGAGAGCCAAAGTGCAGCTATTCAAGATCGATCAGCAG
Downstream sequence
cacctcttagtctaggtagacactttcactggataggtacaggcctttcctacagggtctgagaaggccaccacagtcatttcttccattctgttagata
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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