Basic Information
VIS ID
TVIS10018828
Fusion event
HBV-chr19 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1815
Integrated sequence
ACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACC
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37.55
Start
49543661/49040404 (Hg38)
End
49543661/49040404 (Hg38)
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/30432; hsa-let-7e/Downstream/268393;
Nearest TSS
ENST00000633603/Upstream/3509; ENST00000301408/Downstream/3480;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/20568, chr19-CpG: 99/Downstream/15561
Nearby gene
SNAR-G1
Upstream sequence
TTCAGGGTGACTGGGTCACTGCGGATGCCACCATATCGGTCCCGTATTTCACATTGATAAGGTCCTGTTTCATTTCTCGTGACATTGGGTAGAATGAGGA
Downstream sequence
ACGCCAACCTTTCCCAGAACCACAGGCTTCCAGAATGTTGTAGGGAAACTGCAAAATCCGCGCCTCCACCAGCCTCTCCCAGCGCCAGGTCAatttcaca
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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