Basic Information
VIS ID
TVIS10018829
Fusion event
HBV-chr20 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1809
Integrated sequence
TCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACC| |AGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACA
Host Sequence
Chromosome
chr20
Cytoband
p11.23
Reference genome
GRCh37.55
Start
20369812/20389168 (Hg38)
End
20369812/20389168 (Hg38)
Fragile sites / regions
FRA20A
Nearest miRNA
hsa-mir-103a-2/Upstream/1918477; hsa-mir-1-1/Downstream/5819018;
Nearest TSS
ENST00000382410/Upstream/21047; ENST00000432942/Downstream/123432;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/19207, chr20-CpG: 17/Downstream/63293
Nearby gene
RALGAPA2
Upstream sequence
CTTTTGCCAAAGTTCAGATTTAGTTCTCTGTTGCTTACATCAAGTGAGCAAACATTATATGCTTAGCCTTTGAAATTTCATTTGTAGGCTATCTGCCAAA
Downstream sequence
CTAAGGCTGTCTCCTGCTCATCAGGGATAGGGGCTCCTGACCGCTAGAAGGGTGGCTCGTATGGGGGCTGCCCTGGAGAGAGACGGAGCAAGGGGCACAG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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