Basic Information
VIS ID
TVIS10018833
Fusion event
HBV-chrX integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1825
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chrX
Cytoband
p21.2
Reference genome
GRCh37.55
Start
30082501/30064384 (Hg38)
End
30082501/30064384 (Hg38)
Fragile sites / regions
FRAXC
Nearest miRNA
hsa-mir-23c/Upstream/490026; hsa-let-7f-2/Downstream/2519272;
Nearest TSS
ENST00000429181/Upstream/146921; ENST00000378988/Downstream/151176;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/2200329, chrX-CpG: 30/Downstream/182671
Nearby gene
MAGEB2
Upstream sequence
TCCCCAATGAAGTATGTGTGTGATAAATTATCCTGCATATCTATATGCACACACCCCTATTCACTTAGCTTATCCAAAAAAACTAGAAGCAGCATAGAGG
Downstream sequence
TAATGACCTTTGAAAAATCTCTGTGCAATTTTACACAAGAACTATGCATTAGTCTCCTTGGTATTTAGATTCCCATGTGTCCTAGGGAGTCTACTATTTC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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