DAP3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018835
Fusion event
HBV-DAP3 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
459
End
558
Integrated sequence
GGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATC
Host Sequence
Chromosome
chr1
Cytoband
q22
Reference genome
GRCh37.55
Start
155701733/155731942 (Hg38)
End
155701824/155732033 (Hg38)
Location type
Exon10
Target gene
DAP3
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-1296-5p ; hsa-mir-615-3p ; hsa-mir-324-5p ; hsa-mir-106b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/385497; hsa-mir-1182/Downstream/219240;
Nearest TSS
ENST00000473358/Upstream/2601; ENST00000476444/Downstream/4725;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/42608, chr1-CpG: 54/Downstream/13473
Upstream sequence
GATAATTTTTCATCTCAGTTTGATCTTATCAGGCATCCTGTACCTCTCCACTTGATGATAAAAAATAAAACATACCACTCCGATGGAAAAAAAAATGAAG
Downstream sequence
GTCAAGTCAAAGGAAAATTTGTTTCTACTTAGATTGTTATCCTGTTTAAAGAAAAATATTtttattaatctatgtattttgacataatttcagacttaga
Target sequence
GCATGGAGGCGCCATTGTGTCGGCTTTGAGCCAGACTGGGTCTCTCTTTAAGCCCCGGAAAGCCTATCTGCCCCAGGAGTTGCTGGGAAAG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate