Basic Information
VIS ID
TVIS10018837
Fusion event
HBV-LOC730100 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1461
Integrated sequence
TATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACC| |CTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCC
Host Sequence
Chromosome
chr2
Cytoband
p16.3
Reference genome
GRCh37.55
Start
51936719/51709581 (Hg38)
End
51936719/51709581 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC730100
Nearest miRNA
hsa-mir-1301/Upstream/1013319; hsa-mir-10b/Downstream/992941;
Nearest TSS
ENST00000437798/Upstream/484006; ENST00000435357/Downstream/663537;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/681221, chr2-CpG: 118/Downstream/861684
Nearby gene
MIR4431
Upstream sequence
GTCTCTTTTGTGGCTAATAATCCTGCTTTGGGAGTAGATCTGATTTCTGAAAATCATTTTGTATCCAAAATAATGTAAGCCTGTAAAGGAAAAACCTGAT
Downstream sequence
TAGCTGTAAGAATATTAAATGCCTAGAAAGTCACCTTTTGCAATCTAGACCTTTTTCTGAGCATTGCTGACTTTGTATATTTAAATGTTTAACTGTGCTT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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